Stephen McGowan, MD

Stephen E. McGowan, MD
Professor
Department of Internal Medicine

Welcome

Dr. McGowan's research interests focus on connective tissue biochemistry in the lung.

His current studies examine the regulation of elastin gene expression during lung development, alveolar septal formation, and airway reactivity in vitamin A deficiency.


Recent Publications

Platelet-derived growth factor receptor-alpha (PDGFRα) and Ras-related C3 botulinum toxin substrate-1 (Rac1) regulate mechano-responsiveness of lung fibroblasts.
McGowan SE, McCoy DM.
Am J Physiol Lung Cell Mol Physiol. 2017 Aug 3:ajplung.00185.2017. doi: 10.1152/ajplung.00185.2017. 

Glucocorticoids Retain Bipotent Fibroblast Progenitors during Alveolar Septation in Mice.
McGowan SE, McCoy DM.
Am J Respir Cell Mol Biol. 2017 Jul;57(1):111-120. doi: 10.1165/rcmb.2016-0376OC.

Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice.
McGowan SE, McCoy DM.
Am J Physiol Lung Cell Mol Physiol. 2015 Sep 1;309(5):L463-74. doi: 10.1152/ajplung.00013.2015. Epub 2015 Jul 2.

Defining robustness protocols: a method to include and evaluate robustness in clinical plans.
McGowan SE, Albertini F, Thomas SJ, Lomax AJ.
Phys Med Biol. 2015 Apr 7;60(7):2671-84. doi: 10.1088/0031-9155/60/7/2671. Epub 2015 Mar 13

In search of the elusive lipofibroblast in human lungs.
Ahlbrecht K, McGowan SE.
Am J Physiol Lung Cell Mol Physiol. 2014 Oct 15;307(8):L605-8. doi: 10.1152/ajplung.00230.2014. Epub 2014 Sep 5. Review.

Regulation of fibroblast lipid storage and myofibroblast phenotypes during alveolar septation in mice.
McGowan SE, McCoy DM.
Am J Physiol Lung Cell Mol Physiol. 2014 Oct 15;307(8):L618-31. doi: 10.1152/ajplung.00144.2014. Epub 2014 Aug 22.

Paracrine cellular and extracellular matrix interactions with mesenchymal progenitors during pulmonary alveolar septation.
McGowan SE.
Birth Defects Res A Clin Mol Teratol. 2014 Mar;100(3):227-39. doi: 10.1002/bdra.23230. Epub 2014 Mar 17. Review.

See list of publications at PubMed